Abstract

BackgroundFor different migrant groups living in an area with few people from the same ethnic background is associated with increased psychosis incidence (the ethnic density effect). We set out to answer the question: are there generational differences in this effect? MethodsAnalysis of a population based cohort (2.2 million) comprising all those born 1st January 1965, or later, living in Denmark on their 15th birthday. This included 90,476 migrants from Africa, Europe (excluding Scandinavia) and the Middle East, with 55% first generation and the rest second-generation migrants. Neighbourhood co-ethnic density was determined at age 15 and we adjusted for age, gender, calendar period, parental psychiatric history and parental income. ResultsFor first-generation migrants from Africa, there was no statistically significant difference (p=0.30) in psychosis rates when comparing lowest with highest ethnic density quintiles, whereas the second generation showed a 3.87-fold (95% CI 1.77–8.48) increase. Similarly, for migrants from the Middle East, the first generation showed no evidence of an ethnic density effect (p=0.94) while the second showed a clear increase in psychosis when comparing lowest with highest quintiles, incidence rate ratio (IRR) 2.43 (95% CI, 1.18–5.00). For European migrants, there was some limited evidence of an effect in the first generation, (IRR) 1.69 (95% CI, 1.19–2.40), with this slightly raised in the second: IRR 1.80 (95% CI, 1.27–2.56). ConclusionsWe found strong evidence for an ethnic density effect on psychosis incidence for second-generation migrants but this was either weak or absent for the first generation.

Highlights

  • Migrant groups are consistently shown to have an increased risk of psychotic illness which persists from one generation to the (Bourque et al, 2011; Cantor-Graae and Pedersen, 2013; Cantor-Graae and Selten, 2005)

  • In comparison the crude psychosis incidence rate for native Danes was 7.2 cases per 10,000 person years

  • For the Middle East group there was no statistically significant difference (p = 0.94) for the first generation while the second generation showed a clear increase in psychosis rates, incidence rate ratio (IRR) 2.43, when comparing lowest and highest quintiles

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Summary

Background

For different migrant groups living in an area with few people from the same ethnic background is associated with increased psychosis incidence (the ethnic density effect). Methods: Analysis of a population based cohort (2.2 million) comprising all those born 1st January 1965, or later, living in Denmark on their 15th birthday This included 90,476 migrants from Africa, Europe (excluding Scandinavia) and the Middle East, with 55% first generation and the rest second-generation migrants. Results: For first-generation migrants from Africa, there was no statistically significant difference (p = 0.30) in psychosis rates when comparing lowest with highest ethnic density quintiles, whereas the second generation showed a 3.87-fold (95% CI 1.77–8.48) increase. For migrants from the Middle East, the first generation showed no evidence of an ethnic density effect (p = 0.94) while the second showed a clear increase in psychosis when comparing lowest with highest quintiles, incidence rate ratio (IRR) 2.43 (95% CI, 1.18–5.00). Conclusions: We found strong evidence for an ethnic density effect on psychosis incidence for second-generation migrants but this was either weak or absent for the first generation

Introduction
Sample
Measures
Statistical analysis
Sensitivity analysis
Ethnic density associations compared across generations
Summary of the results
Strengths and limitations
Comparison with previous studies
Interpretation
Implications
Full Text
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