Abstract

Aim: We aimed to investigate the alteration and distribution of seroprevalence of hepatitis B and hepatitis C within the years according to age groups in patients who applied to our hospital. Materials and Methods: The patients have been evaluated for six years retrospectively who were admitted to third step hospital in Istanbul. The duplicate results of patients who submitted more than one application within the same year were excluded from this study. Male and female patients were divided into four age groups as 0-14, 14-25, 25- 49 and over 49 years old. Electrochemiluminescence method (Roche Cobas 6000, Germany) was used for HBsAg and anti-HCV assays. Results: HBsAg positivity was 2.97% and anti-HCV positivity was 1.35%. HBsAg positivity was higher in males, and anti-HCV positivity was higher in females. No significant increase in seroprevalences of anti-HCV and HBsAg was observed during the six years observation period. HBsAg seroprevalences decreased in years especially in 0-14 and 14-25 year-old male groups. HBsAg seroprevalence was not decreased in the other age groups over the years. There was no significant difference in anti-HCV seroprevalence over the years. HBsAg positivity was higher in males and anti-HCV positivity was higher in females. Anti-HCV and HBsAg seroprevalence were not significantly differed over the years. Conclusion: It was remarkable that HBsAg positivity rate had decreased over the years especially in 0-14 and 14-25 year-old males. Seroprevalence of HBsAg did not decrease in years in other age groups. There was no significant difference in the seroprevalence of anti-HCV during the measurement period.

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