Peripheral Nerve Injuries: The Recent Surgical Management Strategies

Abstract

Objectives: Numerous individuals with peripheral nerve injuries (PNIs) have permanent disability, which is a major health concern. There are a number of potential causes of PNIs, including piercing injuries, compression, stretch, and ischemia. These injuries can present with a variety of clinical symptoms. Methodology: In order to clarify the many forms of injury, the peripheral nerve's anatomy is thoroughly explained in this review, which attempts to revisit key PNI ideas. In addition, the specific pathophysiological processes that follow a peripheral nerve damage and the related variables that might either support or undermine the body's ability to regenerate itself depending on PNIs classifications are also mentioned. Next, the recent therapeutic neurosurgical approaches that are accessible in cases of PNIs are described. Results: Following our overview of the previous literatures on neurosurgical strategies for the management of PNIs, we can observe that surgical procedures are unfortunately very expensive and that their use has been limited due to a variety of adverse effects, such as immunosuppression, chromosomal abnormalities, and tumorigenicity. Conclusion: In accordance with the source, location and extent of the injury, there are currently advantages to treating PNIs with both surgical and non-surgical approaches. These days, it is possible to identify innovative techniques with the aid of good information regarding incidences, existing practice, outcomes, and study types. Despite a great deal of research on this topic, full functional recovery is still a problem that has to be solved.