Abstract
BackgroundTissue adhesives are now routinely used for skin closure in various surgeries. This study aimed to evaluate the safety and efficacy of n-butyl-2-cyanoacrylate (NBCA) tissue adhesive in cesarean delivery by comparing it with the safety and efficacy of subcuticular suture closure.Methods and findingsA retrospective chart review was undertaken of all patients who underwent cesarean delivery via Pfannenstiel skin incision. During the study period, a total of 209 patients had NBCA (Histoacryl®) closure and 208 patients had suture closure. Wound complications and Vancouver scar scale (VSS) scores were compared between the 2 groups.ResultsThere were no significant differences between the two groups in indications for cesarean deliveries or number of previous cesarean deliveries. Incidences of wound disruption and infection were also similar between the two closure groups (p = 0.322 and 0.997, respectively). The rate of wound complications was 3.4% in the NBCA group and 5.3% in the suture group. All complications healed uneventfully with topical antibiotics or closure strips. VSS scores at 6–8 weeks after operation were not significantly different between the two groups (p = 0.858). These results were corroborated by propensity score-matching analysis.ConclusionsNBCA may be a useful skin closure of Pfannenstiel skin incisions after cesarean delivery.
Highlights
Cesarean delivery is one of the most commonly performed surgeries worldwide
Rapid removal of the suture can result in weak wound tensile strength, resulting in a widened scar, while late removal can result in scar formation due to inflammation [5]
The skin incision was closed by NBCA tissue adhesive
Summary
Cesarean delivery is one of the most commonly performed surgeries worldwide. About 26% of pregnant women in OECD countries deliver by cesarean [1]. Cesarean delivery requires a relatively long skin incision, and efficient healing of the cesarean wound is a very important determinant of the postoperative satisfaction of the patient. The skin wound from cesarean section is generally closed with surgical staples or sutures [2,3,4]. Staples have the advantage of reducing operative time, they are likely to cause more wound disruption or infection than suture closure [3]. Suture closure is a safe and effective method, but time consuming and operator dependent, and there is a risk of needle stick injury. Tissue adhesives are routinely used for skin closure in various surgeries. This study aimed to evaluate the safety and efficacy of n-butyl-2-cyanoacrylate (NBCA) tissue adhesive in cesarean delivery by comparing it with the safety and efficacy of subcuticular suture closure.
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