Abstract
The abnormal scar is a unique fibrosis disease because it only occurs in humans (Homo sapiens). Researchers now challenge no other animal species, including primates, are found to naturally form scar7, whereas animal models are essential references for human treatment modalities. This study aimed to determine the Modified Vancouver Scar Scale (VSS) score with the addition of collagen density parameters used to assess the scar in experimental animals quantitatively and generates a better assessment of the scar. The cross-sectional analytical survey method was adopted. The experimental animal was Rattus novergicus. The Modified VSS score was applied to assess the normal and abnormal scar data. The Likert categorization guidelines were used to obtain the VSS Score modification score. The collagen density and VSS had a significantly different based on T-test (p <0.05). The differences were also shown by the control and treatment groups. On the correlation analysis, there were the positive coefficient (0.722). The result can be described that the collagen density increases, when the VSS score is high. It also showed the differences based on the score (p <0.05). The Modified VSS score calculation's final results are classified into three groups namely Good (ranged from 0 to 1); Medium (ranged from 2 to 4); and Adverse (ranged from 5 to 6). The Modified VSS score is possibly to be used for the scar assessment to the Rattus novergicus abnormal scar model.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.