Natural deep eutectic solvent assisted synthesis of FeMnO3 entrapped functionalized carbon nanofiber composite: An electrochemical detection of nimesulide

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are a distinguished group of pharmaceuticals with a comprehensive range of beneficial effects. Herein, this work confers the electrochemical detection of NSAIDs drug nimesulide, a prohibited drug in various countries owing to its toxic uncertainties, by employing a hybrid nanocomposite as an efficient sensor. The eco-approachable green synthesis of FeMnO3 through natural deep eutectic solvent (NADES) integrated with f-CNF highlights the remarkable features of obtained hybrid FeMnO3@f-CNF nanocomposite. Green chemistry synthesis methodology boasts well-defined properties in developing hierarchical heterojunctions that use less energy and produce nominal by-products. Analytical and spectroscopical techniques examine the structural-chemical features. The electrochemical determination of nimesulide at the surface of the FeMnO3@f-CNF modified electrode is examined by CV and amperometric (i–t). The distinctive structural architectures of the fabricated FeMnO3@f-CNF provide excellent electrochemical activity due to rapid charge transfer between electrode/electrolyte interfaces. The as-fabricated sensor displays lower Rct value (59.41 Ω·cm2) and detection limit (5.3 nM), dynamic linear range (0.001–244.55 µM), high selectivity (12 interfering compounds), good operational (1000 sec) and cycle stabilities (10 cycles) towards the electrochemical screening of nimesulide which further marks the electrodes viability in the actual sample analysis. Hence, the modification of well-ordered structures of FeMnO3 incorporated with functional attributes of f-CNF mould the hybrid FeMnO3@f-CNF nanocomposite, which can be employed in the future for real-world analysis of drug pollutants in clinical diagnostics.