Abstract
ObjectiveTo assess the effects of two different nutritional mode on the occurrence of ventilator-associated pneumonia (VAP) in patients on mechanical ventilation.Methods70 patients admitted to the ICU and under mechanical ventilation, were randomly divided into the nasointestinal tube group and nasogastric tube group. Patients from both groups received enteral nutrition, using the same nutritional agent, through intubation. The duration of stay in the ICU, duration of mechanical ventilation, incidence of VAP, nutritional state, and survival of the intestinal tract were compared between the two groups.ResultsThe duration of stay in the ICU, duration of mechanical ventilation and incidence of VAP in the nasointestinal tube group was lower than that in the nasogastric tube group (P<0.05). There was an increase in the levels of prealbumin and transferrin in the nasointestinal tube group (P<0.05). However, there were no obvious difference in the nasogastric tube group (P<0.05). The incidence of abdominal distension, diarrhea, regurgitation, aspiration, and hyperglycemia in the nasointestinal tube group was much lower than that in the nasogastric tube group (P < 0.05).ConclusionThis study showed that enteral nutrition delivery using a nasointestinal way can effectively reduce the incidence of VAP and improve the nutritional status of patients under mechanical ventilation.
Highlights
Nosocomial pneumonia is the second most prevalent nosocomial infection in hospital in-patients, with ventilator-associated pneumonia (VAP) being the leading nosocomial infection in patients admitted to the intensive care unit (ICU)
70 patients (42 men, 28 women, age: 52.9 ± 12.4 years, range: 35-70 years) admitted to the ICU of our hospital between January 2016 and November 2017 and who were under mechanical ventilation for more than 48 h were included in this study
VAP is one of the most common complications observed in patients under mechanical ventilation
Summary
Nosocomial pneumonia is the second most prevalent nosocomial infection in hospital in-patients, with ventilator-associated pneumonia (VAP) being the leading nosocomial infection in patients admitted to the intensive care unit (ICU). Studies have shown that the incidence of VAP in mechanically ventilated patients is between 9% and 69%, which is four times higher than that in patients admitted to the normal ward [1]. Enteral nutrition is an important part of the treatment in patients on ventilation, and can improve the nutritional status and immune function in critically ill patients. It is an important factor in the prevention of the occurrence of VAP. The primary objective of this study was to confirm the possible differences in the incidence of VAP resulting from the use of nasogastric and nasointestinal tubes for nutrition delivery in patients under mechanical ventilation.
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