Abstract
Background: Esophageal cancer shared similar risk factor of development with head & neck cancer. 10 to 15% of patients with head and neck cancer harbored a second primary esophageal cancer. Conventionally, endoscopic surveillance is achieved in high risk patients with Lugol chromoendoscopy. Lugol chromoendoscopy, however, can induce significant esophageal spasm and chest pain. Recently, NBI is developed as one of the option to achieve optical chromoendoscopy. This study aimed to compared NBI. Method: We prospectively recruit patients with head and neck cancer or history of squamous esophageal cancer treated with definitive chemoradiotherapy (CRT) for surveillance endoscopy.
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