Abstract
AbstractA new naphthalimide‐based fluorescent probe [(S)‐1 and (S)‐2] employing (S)‐BINOL unit as a chiral responsive group has been designed and synthesized. Ligand (S)‐1 showed greater fluorescence enhancement towards (R)‐amino alcohol and the value of enantiomeric fluorescence difference (ef) ratio reached as high as 7.07 for phenylalaninol while (S)‐phenylalaninol did not show much enhancement in fluorescence, whereas ligand (S)‐2 showed ef value of 4.49 for phenylalaninol. The fluorescence enhancement can be attributed to imine formation and H‐bonding. Further, the R/S chiral selectivity of ligands (S)‐1 and (S)‐2 is opposite. The chiral discrimination ability of (S)‐1 and (S)‐2 was tested via fluorescence, NMR and CD spectral analysis. The results indicated that the sensor (S)‐1 was very promising for use as a fluorescent sensor in determining the enantiomeric composition of α‐amino alcohols.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
