Nanotechnology in Cosmetics and Cosmeceuticals-A Review of Latest Advancements.

Vaibhav Gupta,Mohammed Aldawsari,Mohammad Ansari,Zeenat Iqbal,Keshav Kumar,Sradhanjali Mohapatra,Harshita Mishra,Uzma Farooq,Ahmed Alalaiwe,Mohd Mirza

doi:10.3390/gels8030173

Abstract

Nanotechnology has the potential to generate advancements and innovations in formulations and delivery systems. This fast-developing technology has been widely exploited for diagnostic and therapeutic purposes. Today, cosmetic formulations incorporating nanotechnology are a relatively new yet very promising and highly researched area. The application of nanotechnology in cosmetics has been shown to overcome the drawbacks associated with traditional cosmetics and also to add more useful features to a formulation. Nanocosmetics and nanocosmeceuticals have been extensively explored for skin, hair, nails, lips, and teeth, and the inclusion of nanomaterials has been found to improve product efficacy and consumer satisfaction. This is leading to the replacement of many traditional cosmeceuticals with nanocosmeceuticals. However, nanotoxicological studies on nanocosmeceuticals have raised concerns in terms of health hazards due to their potential skin penetration, resulting in toxic effects. This review summarizes various nanotechnology-based approaches being utilized in the delivery of cosmetics as well as cosmeceutical products, along with relevant patents. It outlines their benefits, as well as potential health and environmental risks. Further, it highlights the regulatory status of cosmeceuticals and analyzes the different regulatory guidelines in India, Europe, and the USA and discusses the different guidelines and recommendations issued by various regulatory authorities. Finally, this article seeks to provide an overview of nanocosmetics and nanocosmeceuticals and their applications in cosmetic industries, which may help consumers and regulators to gain awareness about the benefits as well as the toxicity related to the continuous and long-term uses of these products, thus encouraging their judicious use.

Highlights

Licensee MDPI, Basel, Switzerland.Nanotechnology and nanodelivery systems are innovative areas of science that comprise the design, characterization, manufacturing, and application of materials, devices, and systems at the nanoscale level (1–100 nm)
The introduction of newer advancements and novel drug delivery systems make cosmetics and cosmeceuticals more popular with increased market share. These cosmetics are an indispensable part of the daily routine; further, the introduction of nanotechnology to cosmetics has enhanced its acceptance among users all around the world
Its associated toxicity owing to its penetrability is a major concern that is often overlooked, leading to adverse health issues

Summary

Introduction

Nanotechnology and nanodelivery systems are innovative areas of science that comprise the design, characterization, manufacturing, and application of materials, devices, and systems at the nanoscale level (1–100 nm). Nanotechnology, being recognized as one of the revolutionizing technologies, is extensively studied in the area of cosmetics and cosmeceuticals [1,2]. The incorporation of nanotechnology has led to advancements in cosmetic science, resulting in increased consumer demand throughout the world [3]. Nanomaterials are attracting attention in this area, as they offer greater advantages over traditionally used cosmetic products. The amalgamation of nanomaterials has greatly contributed to the global increase in the market share of pharmaceuticals and cosmetics

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