Nanostructure-Based Surface-Enhanced Raman Spectroscopy Techniques for Pesticide and Veterinary Drug Residues Screening.

Abstract

Pesticide and veterinary drug residues in food and environment pose a threat to human health, and a rapid, super-sensitive, accurate and cost-effective analysis technique is therefore highly required to overcome the disadvantages of conventional techniques based on mass spectrometry. Recently, the surface-enhanced Raman spectroscopy (SERS) technique emerges as a potential promising analytical tool for rapid, sensitive and selective detections of environmental pollutants, mostly owing to its possible simplified sample pretreatment, gigantic detectable signal amplification and quick target analyte identification via finger-printing SERS spectra. So theoretically the SERS detection technology has inherent advantages over other competitors especially in complex environmental matrices. The progress in nanostructure SERS substrates and portable Raman appliances will promote this novel detection technology to play an important role in future rapid on-site assay. This paper reviews the advances in nanostructure-based SERS substrates, sensors and relevant portable integrated systems for environmental analysis, highlights the potential applications in the detections of synthetic chemicals such as pesticide and veterinary drug residues, and also discusses the challenges of SERS detection technique for actual environmental monitoring in the future.