Nanosponges- A Versatile Approach of Drug Delivery System

Abstract

With the escalating number of diseases, an opportunistic target drug delivery system is needed. Nanosponges (NS) are nanosized drug delivery systems having three-dimensional (3D) configurations, fabricated by crosslinking of polymers to ensnare a wide assortment of drugs. These small particles move inside the body till they arrive at the target site and deliver the medication in a specific and controlled way. They can ensnare (entrap) both hydrophilic and hydrophobic moieties in a smarter manner and improve the solubility and bioavailability of drugs. NS have been utilized to examine the medication conveyance by oral, parenteral, and topical routes. Another significant property of NS is that they can work on the solvency of ineffectively water-soluble moieties and are utilized for the storage of gases, and proteins as well as for the removal of toxins from the systemic circulation. The present review highlights the types of nanosponges, their methods of preparation, characterization, and applications in drug delivery.