Abstract
Nanotechnology is a fast growing area of research that aims to create nanomaterials or nanostructures development in stem cell and tissue-based therapies. Concepts and discoveries from the fields of bio nano research provide exciting opportunities of using stem cells for regeneration of tissues and organs. The application of nanotechnology to stem-cell biology would be able to address the challenges of disease therapeutics. This review covers the potential of nanotechnology approaches towards regenerative medicine. Furthermore, it focuses on current aspects of stem- and tissue-cell engineering. The magnetic nanoparticles-based applications in stem-cell research open new frontiers in cell and tissue engineering.
Highlights
Nanotechnology and nanoengineering are the science and engineering involved in the design, synthesis, characterization, and application of materials and devices
The review of synergism between stem-cell biology and biomaterial technology recapitulates the molecular events involved in the production, clearance and interaction of molecules involved in regeneration/replacements of tissue/organs for novel clinical therapeutics [23]
Nanobiological research is a speculating area of interest in many countries and its relevance within physical sciences, molecular engineering, biology, biotechnology, and medicine is expected to increase in the future
Summary
Nanotechnology and nanoengineering are the science and engineering involved in the design, synthesis, characterization, and application of materials and devices. These materials and devices with a high degree of functional specificity interact with cells and tissues at a molecular (i.e. subcellular) level, thereby allowing a degree of integration of technology with medicine and physiology that was at all not previously attainable. Nanoparticles were used for specific and controlled delivery of growth factors, drugs and DNA molecules to the target site, whereas, nanofibres are used for preparing tissue scaffolds and for modifying the surface of implantable materials, nanodevices such as biosensors [3].
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