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Abstract
AbstractCopper(I)‐catalyzed N‐arylation (both N1‐ and N3‐) of hydantoins with diaryliodonium salts as aryl partners at room temperature is reported. The transformation allows diverse scopes on both hydantoins and diaryliodonium salts delivering functionalized N3‐arylated products under mild reaction conditions. The presence of hydrogens at C5‐ and N1‐ position of the hydantoin does not lead to other side products. Chiral hydantoins can also be synthesized via this methodology. Sterically complicated ortho‐substituted diaryliodonium salts are tolerated and delivered challenging ortho‐arylated products. In addition, this strategy can also be effectively extended to N1‐arylation of hydantoins.
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