Abstract
Chemical screening of bio-resources coupled with dereplication is an efficient method to discover new chemical scaffolds. In this study, twenty Irish marine sponges were subjected to rapid SPE fractionation followed by their chemical screening based on 1H NMR and HPLC-DAD-ELSD profiles. A fraction obtained from the sponge Hymeniacidon perlevis had the most promising profile, and further purifications and spectroscopic investigations including HRMS, 1D and 2D NMR led to the identification of a new metabolite N-didehydrotyrosine (1) and the known compound N9-methyladenine (2).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
