Abstract
3 cases of vascular leiomyoma arising in the oral area were examined. The first case was a 72-year-old male showing slight swelling of the median palate. The second case was a 60-year-old male showing a red bean sized elastic hard mass in the right lower lip. The third case was a 57-year-old male with an appearance in the left nose vestibule.Histologically, all cases revealed that polygonal shaped smooth muscle like tumor cells proliferate perivascular area and formed small nodules with entangled muscle fibers. An immunohistochemical analysis showed that strong positive reaction for the VIIIth factor-related antigen in cord-like arranged tumor cells and in angioendothelial cells. The actin was positive for outer layer cells of the vesseles.Positive reaction for desmine was observed in fibroblastoid cells. The vimentin was positive for angioendothelial cells and most of the tumor cells.
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