Abstract
Recent studies have shown that hepatitis B virus exists not only in the blood but also in the saliva and other body fluids. They also pointed out the possibility of transmission through these fluids.Because of this we tried to detect hepatitis B surface antigen (HBsAg) in saliva, urine and its alteration throughout the day in asymptomatic carrier patients.Salivary and urinary HBsAg were shown by radioimmunoassay in five patients. After rinsing the mouth, the samples of mixed saliva were collected in the morning on rising, before lunch and before sleeping from each carrier patient. Urine was collected only in the morning.Each time, the HBsAg was found in the saliva of 3 out of 5 carrier patients, although in the other two patients it was detected only once or twice in a day.All saliva samples were tested for occult blood but it was not related to the detection of HBsAg.Urinary HBsAg was not found in all patients.
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