Abstract
We evaluated the association between portal hypertensive gastropathy and portal hemodynamics. The subjects were 35 patients with liver cirrhosis complicated by esophageal varices in whom the clinical course were observed for 3 years. They were classified into the group who developed a spleno-renal shunt during the course and that who did not. The incidence of portal hypertensive gastropathy before observation was similar between the two groups. Changes in portal hypertensive gastropathy during the course were slighter in the spleno-renal shunt group than the non-shunt group. Since no difference were observed in the size of spleen, the diameter of the main trunk of the portal vein, or blood biochemical findings between the two groups during the observation period, the development of the spleno-renal shunt, ie, the state of the development of the collateral circulation seems to be involved in the development of portal hypertensive gastropathy.
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