ルイス酸による炭化水素官能基の活性化を基軸とする新触媒反応の開発

Abstract

Over a long period of time, in the field of synthetic organic chemistry, Lewis acids have been used mainly as activators for heteroatom-containing functional groups such as carbonyls, imines and halides. In contrast to the traditional approach utilizing such Lewis acid chemistry, we have been focusing on developing new catalytic reactions on the basis of activation of hydrocarbon functional groups by Lewis acids. In order to activate effectively the hydrocarbon functional groups classified into C≡C, C=C, C−C and C−H, an appropriate choice of a Lewis acid catalyst is a crucial aspect. Herein, I disclose our recent achievements based on the Lewis acid-activated hydrocarbon functional groups.