Abstract
From 1977 to 1996, 199 patients (167 males, 32 females) with a mean age of 66 years having previously untreated supraglottic carcinoma underwent curative treatment at the Kurume University Hospital. In this paper, the sites of extension were examined, and their influence upon the frequency of neck metastasis and distant metastasis were analyzed.The overall, five-year survival rate as determined by the Kaplan-Meier method was 75.6%. With respect to invasive site, for patients with subglottic and piriform sinus invasion, the five-year cause-specific survival rates were 59.7% and 41.4%, respectively. The 5-year local control rate of the tumor was 81.7%, and for patients with lesions confined to the supraglottis was 88.3%. The frequency of neck metastasis for patients with lesions invading the lateral wall of the oropharynx and piriform sinus were 78% and 89%, respectively. The frequency of distant metastasis in patients with lesion invading the piriform sinus was 36%. These results suggest that chemotherapy may be neccessary for cases with tumors invading the piriform sinus.
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