Abstract
Background: Changes in lifestyle have led to an increase in the global incidence of type 2 diabetes mellitus (T2DM). In Mexico there are 6.4 million type two diabetic patients. It is widely recognized that insulin resistance and T2DM are associated with low‐grade chronic inflammation. There is evidence about the beneficial effect of polyunsaturated fatty acids (PUFA) n‐3 in patients with chronic inflammatory diseases. Objective: To investigate the relationship between habitual fatty acid intake and circulating biomarkers of inflammation in patients with T2DM in the population of the State of Mexico. Methods: We conducted a cross sectional study in a sample of 120 diabetic adults to whom we performed anthropometric assessments (BMI, waist circumference, body fat percentage and blood pressure) as well as PUFA dietary intake, biochemical analyses and inflammation biomarkers (IFN‐γ, TNF‐ α, IL‐1 β). Results: A low intake of n‐3 was found in our population (0.68 ± 0.55 g/day). Moreover higher serum concentrations of pro‐inflammatory cytokines were present. No correlations between the regular consumption of fatty acids and lipid profile and biomarkers of inflammation were found. Conclusions: Mexican diabetic patients had a low PUFA intake, but there is no association between the consumption of PUFA and lipid profile or pro‐inflammatory or anti‐inflammatory biomarkers.
Published Version
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