Abstract
Background Changes in the longitudinal relaxation time (T1) of the myocardium are considered an important imaging-based biomarker to detect and quantify diffuse fibrosis. Several sequences have been suggested to measure myocardial T1 values [1]. However, T1 measurements are often influenced by the presence of intramyocardial or epicardial fat [2,3,4]. The aim of this study was to minimize the effect of fat in T1 mapping by the use of a water selective inversion pulse and to investigate the impact of this spectrally-selective inversion pulse on T1 measurements in the presence of field inhomogeneities.
Highlights
Changes in the longitudinal relaxation time (T1) of the myocardium are considered an important imaging-based biomarker to detect and quantify diffuse fibrosis
Myocardial T1 mapping with spectrally-selective inversion pulse to reduce the influence of fat Maryam Nezafat1,2*, Sébastien Roujol2, Jihye Jang3, Tamer Basha2,4, Rene M Botnar1
The aim of this study was to minimize the effect of fat in T1 mapping by the use of a water selective inversion pulse and to investigate the impact of this spectrally-selective inversion pulse on T1 measurements in the presence of field inhomogeneities
Summary
Changes in the longitudinal relaxation time (T1) of the myocardium are considered an important imaging-based biomarker to detect and quantify diffuse fibrosis. Several sequences have been suggested to measure myocardial T1 values [1]. T1 measurements are often influenced by the presence of intramyocardial or epicardial fat [2,3,4]. The aim of this study was to minimize the effect of fat in T1 mapping by the use of a water selective inversion pulse and to investigate the impact of this spectrally-selective inversion pulse on T1 measurements in the presence of field inhomogeneities
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