Myocardial performance index is associated with Systematic Coronary Risk Estimation (SCORE) system in chronic coronary syndrome

Abstract

Objective: The Systematic Coronary Risk Estimation (SCORE) system is used to determine 10-year cardiovascular risk. Myocardial performance index (MPI), a well-accepted echocardiographic parameter, is used to provide an information about global function of the ventricle. We aimed to investigate the relationship between MPI and SCORE. Methods: A total of 168 participants with chronic coronary syndrome (CCS) presented to cardiology outpatient clinic between 1 June and 31 December 2020 were retrospectively enrolled in the study. Cardiovascular risk estimation was calculated by SCORE assessment. The participants were divided into two groups as 46 patients with low cardiovascular risk, and 122 patients with moderate-high-very high risk, according to the SCORE. Laboratory parameters and echocardiography findings of the patients were recorded. Results: There was no difference in body mass index, office systolic, and diastolic blood pressure between the groups. While blood glucose was 94.5 (83.0-110.3) in the low-risk group, it was 101.0 (90.0-130.5) in the moderate-high risk patient group (p = 0.007). Similarly, Urea, creatinine, lactate dehydrogenase, total cholesterol, NT pro-BNP, and Troponin T in the moderate-high risk group were significantly higher than was the low-risk group. MPI was significantly higher in the moderate-high risk patient group (p <0.001). MPI (OR = 2.358, 95 % CI: 1.033-5.382, p = 0.042), urea (OR = 1.090, 95 % CI: 1.019-1.166, p = 0.012), and glucose (OR = 1.023, 95 % CI: 1.003-1.043, p = 0.025) were independently associated with the moderate-high SCORE. Conclusion: We found that MPI predicted moderate-high SCORE system. Further studies are warranted to better clarify the association of SCORE with echocardiographic parameters including MPI.