Abstract
Fungi generally and mushrooms secondary metabolites specifically represent future factories and potent biotechnological tools for the production of bioactive natural substances, which could extend the healthy life of humanity. The application of microbial secondary metabolites in general and mushrooms metabolites in particular in various fields of biotechnology has attracted the interests of many researchers. This review focused on Lentinus, Pleurotus, and Tremella as a model of edible mushrooms rich in therapeutic agents that have known medicinal applications.
Highlights
Mushrooms have been used as a traditional medicine for the last few eras
The fungi belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine in the treatment and prevention of several diseases such as cancer, hypertension, and diabetes, among many other conditions
Species belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine, until modern days in the treatment, and prevention of several diseases such as cancer, hypertension, chronic bronchitis, asthma, and others [14, 15]
Summary
Mushrooms have been used as a traditional medicine for the last few eras. Mushrooms as higher Basidiomycetes and Ascomycetes contain secondary metabolites in their fruit bodies, cultured mycelium, and cultured broth. The fungi belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine in the treatment and prevention of several diseases such as cancer, hypertension, and diabetes, among many other conditions. More than 140 biologically active triterpenoids and 200 polysaccharides, as well as proteins and various metabolites, have been isolated from the fruiting bodies, mycelium and spores of different species of Ganoderma. Species belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine, until modern days in the treatment, and prevention of several diseases such as cancer, hypertension, chronic bronchitis, asthma, and others [14, 15]. The present review focuses on various edible medicinal species of mushrooms belong to genera: Lentinus, Pleurotus, and Tremella, along with their chemical composition, biologically active compounds isolated, and their pharmacological potential
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