Editorial: Microbial Secondary Metabolites: Recent Developments and Technological Challenges.

Bhim Pratap Singh,Wen-Jun Li,Susana Rodriguez-Couto,Mostafa E Rateb,Maria De Lourdes Teixeira De Moraes Polizeli Polizeli

doi:10.3389/fmicb.2019.00914

Abstract

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Editorial: Microbial Secondary Metabolites: Recent Developments and Technological Challenges.

Highlights

Microbial secondary metabolites, like antibiotics, pigments, growth hormones, antitumor agents, and others, are not essential for the growth and development of microorganism, but they have shown a great potential for human and animal health (Ruiz et al, 2010)
These bioactive compounds are mainly produced by the activation of cryptic gene clusters which are not active under normal conditions and, the expression of these clusters would be helpful in the exploitation of the chemical diversity of microorganisms (Pettit, 2011; Xu et al, 2019)
Several reports on microbial secondary metabolites have been published in recent years (Passari et al, 2017; Zothanpuia et al, 2018; Overy et al, 2019), our understanding to enhance the production of bioactive secondary metabolites is still limited

Summary

Introduction

Like antibiotics, pigments, growth hormones, antitumor agents, and others, are not essential for the growth and development of microorganism, but they have shown a great potential for human and animal health (Ruiz et al, 2010). Microbial Secondary Metabolites: Recent Developments and Technological Challenges Among the microorganisms producing the above-mentioned compounds, bacteria, including actinobacteria, and fungi produce a diverse array of bioactive small molecules with significant potential to be used in medicine (O‘Brien and Wright, 2011).

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