Abstract
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Highlights
Simultaneous vaccination against porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae can decrease the efficacy of the separate vaccination
The challenge test with both porcine reproductive and respiratory syndrome virus and M. hyopneumoniae was performed in experimental conditions on swine groups with different immune protection against M. hyopneumoniae
The results suggest that M. hyopneumoniae initiates the pathogenic chain of M. hyopneumoniae - porcine reproductive and respiratory syndrome virus co-infection
Summary
The immunization against M. hyopneumoniae undoubtedly influences the development of porcine reproductive and respiratory syndrome virus - M. hyopneumoniae co-infection, the interactions between infectious agents and immune defense depend on the qualitative and quantitative parameters of immunity. These interactions are multi-factorial and too complicated for an absolutely correct prognosis. The assumption is that PRRS virus always comes as the first, leaving the pig’s immune system vulnerable to secondary bacterial infections, which leads to Mycoplasma hyopneumoniae (M. hyopneumoniae) caused secondary infection This is often followed by the swine influenza virus (SIV) and by minor infections (Pol et al.1997; Solano et al 1997)
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