Abstract
A sudden mid dramatic rise in the level of serum CPK occurs at the haemolytic crisis period of chronic copper poisoning. This suggests that changes occur in the muscle cell membrane, as well as in the liver, erythrocyte, kidney and brain, which have been previously recorded. There is no evidence for muscle lesions during the passive accumulating phase of copper toxicity, and once over the crisis, the serum CPK rapidly returns to normal levels.
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