Abstract

A 31-year-old man was admitted to our hospital due to recurrent abdominal pain and intermittent melena for 9 years. He also suffered from skin thickening and digital clubbing since adolescence (Fig. 1A and B). He denied intake of non-steroidal, anti-inflammatory drugs. Blood tests revealed normocytic normochromic anemia (hemoglobin, 110 g/dL). Other examinations such as T-SPOT.TB, autoantibody biomarkers, cytomegalovirus, Epstein-Barr virus, and growth hormone level were normal. X-ray showed irregular cortical thickening of the tibiofibular and hand (Fig. 1C).

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