Abstract
Multiple paragangliomas involving carotid body and vagal region: A sporadic case
Highlights
Paragangliomas are neuroendocrine tumors that represent 0.012% of all tumors [1]
As opposed to carotid body tumors, vagal paragangliomas are located more cephalad in the neck, between the jugular vein and the internal carotid artery, sometimes extending to the base of the skull through the jugular foramen or posteriorly to the mastoid tip [7]
The present case report represents the sporadic case of multiple paragangliomas involving the carotid body and vagal region
Summary
Paragangliomas are neuroendocrine tumors that represent 0.012% of all tumors [1]. Paragangliomas arise from extra-adrenal paraganglia, microscopic islands of cells derived embryonically from the neural crest cells of the autonomic nervous system [1,2]. Carotid body tumors are the most common paraganglioma often present as slow growing, non- tender neck masses located just anterior to the sternocleidomastoid muscle at the level of the hyoid [4]. Carotid body paragangliomas arise at the bifurcation of the internal and external carotid arteries [5]. As opposed to carotid body tumors, vagal paragangliomas are located more cephalad in the neck, between the jugular vein and the internal carotid artery, sometimes extending to the base of the skull through the jugular foramen or posteriorly to the mastoid tip [7]. The present case report represents the sporadic case of multiple paragangliomas involving the carotid body and vagal region. The present study, to our best knowledge, is the second study in the world which reported the multiple paragangliomas involving the carotid body and vagal region
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