Multimodal Therapy for Recalcitrant Cutaneous Fusarium Solani Infection in a Patient with Hyper-IgE Syndrome

Abstract

Hyper IgE Syndrome (HIES) is an inherited immunodeficiency syndrome with an increased susceptibility to cutaneous fungal infections. While systemic antifungals are often the therapy of choice, many non-pharmacologic treatment options have been shown to improve clearance of these infections. We report the treatment course of cutaneous Fusarium Solani infection in an 8-year-old male with HIES with progression despite a series of systemic antifungals.