Abstract
Bio-atomic force microscopy (AFM) is an eminent tool for quantitative nanomechanical property mapping, high resolution imaging of various biomolecules, proteins, DNA, live cells in their physiological environment at single molecule level. Although atomic force microscopy was primarily developed for generating three-dimensional image of the substrate, development of PeakForce QNM mode has revolutionized that by allowing users to obtain maps of nanomechanical properties such as adhesion, Young’s modulus, and deformation with high resolution, and acquisition speed.
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