Multilevel Clustering-Evolutionary Random Support Vector Machine Cluster Algorithm-Based Functional Magnetic Resonance Imaging in Diagnosing Cerebral Ischemic Stroke

Abstract

This study was to explore the value of the blood oxygenation level dependent-functional magnetic resonance imaging (BOLD-fMRI) image classification based on the multilevel clustering-evolutionary random support vector machine cluster (MCRSVMC) algorithm in the diagnosis and treatment of patients with cognitive impairment after cerebral ischemic stroke (CIS). The MCRSVMC algorithm was optimized using a clustering algorithm, and it was compared with other algorithms in terms of accuracy (ACC), sensitivity (SEN), and specificity (SPE) of classifying the brain area images. 36 patients with cognitive impairment after CIS and nondementia patients were divided into a control group (drug treatment) and an intervention group (drug + acupuncture) according to different treatment methods, with 18 cases in each group. The changes in regional homogeneity (ReHo) of BOLD-fMRI images and the differences in scores of the Montreal Cognitive Assessment Scale (MoCA), scores of Loewenstein Occupational Therapy Cognitive Assessment (LOTCA), and scores of Functional Independence Measure (FIM) between the two groups of patients were compared before and after treatment. The results revealed that the average classification ACC, SEN, and SPE of the MCRSVMC algorithm were 84.25 ± 4.13%, 91.07 ± 3.51%, and 89 ± 3.96%, respectively, which were all obviously better than those of other algorithms ( P < 0.01 ). When the number of support vector machine (SVM) classifiers and the number of important features were 410 and 260, respectively, the classification ACC of MCRSVMC algorithm was 0.9429 and 0.9092, respectively. After treatment, the MoCA score, LOTCA score, and FIM score of the patients in the intervention group were higher than those of the control group ( P < 0.05 ). The ReHo values of the right inferior temporal gyrus and right inferior frontal gyrus of patients in the intervention group were much higher than those of the control group ( P < 0.05 ). It indicated that the classification ACC, SEN, and SPE of the magnetic resonance imaging (MRI) based on the MCRSVMC algorithm in this study were greatly improved, and the acupuncture method was more effective in the treatment of patients with cognitive dysfunction after CIS.