Abstract
Bone Tissue Engineering In article number 2107924, Kai Jiao, Franklin R. Tay, Li-na Niu, and co-workers present RNA-ACP nanomachines that induce extrafibrillar and intrafibrillar mineralization of collagen fibrils and regenerate new bone in a dynamic and programmable manner. These multifunctional nanomachines are comparable to the function of osteoblasts and bring new opportunities and challenges to bone tissue engineering.
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