Abstract

A long historical experience of monofrequency rheoencephalography (REG) showed its limited capabilities. The new approach ispresented - multifrequency REG that is REG record ing simultaneously at three frequencies - 16, 100 and 200 kHz. The d ifferent brain impedances received were analysed on the base of equivalent electrical circuits of brain tissue. First, this enables to calculate intra-extracellu lar electrical co mponent for evaluation of brain tissue hydration state by means of an original co mputational method. Second, dynamic cooperative analysis of mu lti -REG and transcranial Doppler pulsations provides the indices of intracranial CSF mobility (CSFm) and cranial co mpliance (CCe). Th ird, spectral analysis of processes recorded provides valuable information of regulatory processes involved. The application of this new approach to investigation of intracranial circu lation in healthy persons of different aging groupos and in neurosurgical patients showed its promising effectiv ity.

Highlights

  • In the midd le of the Twentieth Century two alternative methods were developed for the study of cerebral circulation

  • The multi-REG as was shown in the investigations of different aging groups is capable of much more subtle evaluation of the relations of liquid med ia inside the cranium. This is evident in the results presented of investigations of different aging+ groups combined with results received of cerebrospinal flu id (CSF) dynamics

  • The redemption for REG was its marriage to transcranial Dopplerography (TCD) wh ich opened new possibilities for the study of CSF dynamics

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Summary

Introduction

In the midd le of the Twentieth Century two alternative methods were developed for the study of cerebral circulation. The second was derived fro m a method based on measurement of electricalimpedanc e of biolog ical t issues or monitoring of electrical resistance between electrodes placed on different regions of the human body, including the head which had first been known as electroplethysmography and as rheography or REG[2,3]. Depending on the body region, modifications of this method were named after the specific organ being investigated. In the context of the present paper, dealing with investigations of fluid circulation through the brain, the term Rheoencephalography or REG will be used. Theadvantage of this method is that it is dynamic. The obvious disadvantage is the data received can only be evaluated comparatively

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