Multi-frequency microstructure of ictal high frequency oscillation (60-170Hz) in epilepsy patients: magnetoencephalography (MEG) study

Abstract

Event Abstract Back to Event Multi-frequency microstructure of ictal high frequency oscillation (60-170Hz) in epilepsy patients: magnetoencephalography (MEG) study Yongho Kwak1*, Huije Che1, Bong-Soo Kim2, Eunyoung Kim1, June S. Kim2 and Chun K. Chung2 1 MEG-Center, Seoul National University Hospital, South Korea 2 Seoul National University College of Medicine, MEG Center, Department of Neurosurgery, South Korea The pathological excessive synchronous neuronal activity generates coherent high frequency oscillations (HFOs) before and during a seizure. Recent studies have reported the presence of HFOs as a good indicator for the epileptogenic zone. However, their internal dynamics has been poorly understood especially during a seizure. In this study, we present detailed internal dynamics of ictal HFOs (50-200Hz) from 12 epilepsy patients (30.2±13.6 years old, 18 seizures) using MEG (600Hz sampling rate). We found that ictal HFOs were composed of diverse high frequency bands that could be discriminated by their wave form. This finding suggests that a seizure could recruit several independent local synchronous networks and that MEG could discriminate the micro-structure of HFOs. Conference: Biomag 2010 - 17th International Conference on Biomagnetism , Dubrovnik, Croatia, 28 Mar - 1 Apr, 2010. Presentation Type: Poster Presentation Topic: Epilepsy Citation: Kwak Y, Che H, Kim B, Kim E, Kim JS and Chung CK (2010). Multi-frequency microstructure of ictal high frequency oscillation (60-170Hz) in epilepsy patients: magnetoencephalography (MEG) study. Front. Neurosci. Conference Abstract: Biomag 2010 - 17th International Conference on Biomagnetism . doi: 10.3389/conf.fnins.2010.06.00384 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 08 Apr 2010; Published Online: 08 Apr 2010. * Correspondence: Yongho Kwak, MEG-Center, Seoul National University Hospital, Seoul, South Korea, kwak@meg.re.kr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Yongho Kwak Huije Che Bong-Soo Kim Eunyoung Kim June S Kim Chun K Chung Google Yongho Kwak Huije Che Bong-Soo Kim Eunyoung Kim June S Kim Chun K Chung Google Scholar Yongho Kwak Huije Che Bong-Soo Kim Eunyoung Kim June S Kim Chun K Chung PubMed Yongho Kwak Huije Che Bong-Soo Kim Eunyoung Kim June S Kim Chun K Chung Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.