Abstract
Peritoneal mesothelioma is a rare cause of a peritoneal mass in adults and can occur in malignant or benign forms. Compared to the pleural variant of mesothelioma, the peritoneal form is understudied due to the small number of reported cases. We present a case of an 84-year-old male with a history of asbestos exposure who initially presented for an aggravated hernia, was found to have an incidental mass on imaging, and ultimately was diagnosed with malignant peritoneal mesothelioma (MPM)1 likely related to prior asbestos exposure. This case study will provide a review of literature and discuss the role of imaging for MPM.
Highlights
Malignant peritoneal mesothelioma is an extremely rare form of malignant mesothelioma
We present a case of an 84-year-old male with a history of asbestos exposure who initially presented for an aggravated hernia, was found to have an incidental mass on imaging, and was diagnosed with malignant peritoneal mesothelioma (MPM)[1] likely related to prior asbestos exposure
A study showed that loss of BAP1 alone without the loss of NF2 and CDKN2A was linked to MPM, suggesting that pleural and peritoneal mesotheliomas have distinct genomic features[10]
Summary
Malignant peritoneal mesothelioma is an extremely rare form of malignant mesothelioma. Studies showing different gene expression profiles of pleural and malignant mesotheliomas suggest differences[4] Since it is an extremely rare disease, there is no data available from randomized controlled studies regarding the imaging findings and treatment options for MPM. Review of social history during the multidisciplinary tumor board discussion confirmed prior asbestos exposure This occupational exposure history, along with the colonoscopy showing no evidence of primary colon cancer, raised the concern for malignant mesothelioma as a possible etiology of the pelvic mass. It was decided surgical management was the best approach to obtain definite tissue diagnosis and alleviate regional mass effect. The patient expired about a month after surgery secondary to cardiac arrest at long term acute care hospital
Published Version (Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have