Abstract
BackgroundTo retrospectively compare the diagnostic accuracy of magnetic resonance imaging (MRI) and multidetector-row computed tomography (MDCT) in the assessment of the mandibular invasion by squamous cell carcinoma (SCC) having histopathological exams as standard of reference.Materials and methodsInstitutional review board approval with a waiver of informed patient consent was obtained. Of the 147 patients selected from our database who underwent surgical excision of a tumour arising into the oral cavity, thirty-six patients (26 men, 10 women; mean age, 56 years; range, 30-75 years) with hystologically proven SCC who performed both a preoperative MRI and MDCT, composed our final study population.Images were qualitatively analyzed in consensus by two expert radiologist in head and neck imaging. Sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) were assessed for both MRI and MDCT.Differences in sensitivity, specificity, positive and negative predictive values were calculated at a statistical significance of p < .05.ResultsThe sensitivity, the specificity and the accuracy of MRI and MDCT in the detection of the mandibular involvement were respectively 93%, 82%, 86% and 79%, 82%, 81%, while the positive predictive value (PPV) and negative predictive value (NPV) were respectively 76%, 95% and 73%, 86%. There wasn't any statistically significant difference in overall diagnostic accuracy between MRI and MDCT in the evaluation of mandibular tumour invasion (p > .05).ConclusionMRI showed to have a higher sensitivity compare to MDCT in the assessment of mandibular involvement from SCC arising in the oral cavity although none statistically significant differences were noted.
Highlights
To retrospectively compare the diagnostic accuracy of magnetic resonance imaging (MRI) and multidetector-row computed tomography (MDCT) in the assessment of the mandibular invasion by squamous cell carcinoma (SCC) having histopathological exams as standard of reference
The sensitivity, the specificity, the accuracy, positive predictive value (PPV) and negative predictive value (NPV) of MRI and MDCT in the assessment of mandibular involvement are reported in table 2
MRI showed a trend to have an higher sensitivity compare to MDCT none statistically significant difference was noted for either sensitivity or specificity (p > .05) (Figure 1, Figure 2, Figure 3)
Summary
To retrospectively compare the diagnostic accuracy of magnetic resonance imaging (MRI) and multidetector-row computed tomography (MDCT) in the assessment of the mandibular invasion by squamous cell carcinoma (SCC) having histopathological exams as standard of reference. Multidetector-row computed tomography (MDCT) and Magnetic Resonance Imaging (MRI) represent the routine imaging modalities for the pre-operative tumour staging of oral and oropharyngeal squamous cell carcinoma (SCC). These techniques provide multiple informations regarding (i) the extension of the tumour beyond the midline lingual septum, (ii) the deep extension and/or (iii) the infiltration of the mandible, considering either the cortical or medullary portion [7,8,9], all of them considered very important points for treatment planning [10,11,12]. Despite these studies varied widely, at our careful review of the literature data, MRI is resulted superior to MDCT in the evaluation of the medullary involvement while MDCT is resulted more accurate compare to MRI in the visualization of small cortical bone erosions [4,7,9]
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