Multicomponent synthesis of pyrazole-3-one under mild conditions using an effective novel ceria-doped copper nanocatalyst

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Synthesis of pyrazole-3-one derivative was successfully catalyzed by a copper nanocatalyst that had been doped with cerium. With outstanding yields of pyrazol- 3-one derivatives, this approach has been applied to a wide range of substrates including electrophilic and sterically hindered aromatic aldehydes. The remarkable selectivity under mild conditions of this commercially available inexpensive catalyst is an attractive feature of this method.