Abstract
Background Cardiac magnetic resonance (CMR) perfusion imaging yields high diagnostic accuracy for the detection of coronary artery disease (CAD) [1]. However, standard 2D multislice CMR perfusion techniques only provide limited coverage and hence prohibit computation of myocardial ischemic burden. Recently, two single-center 3D CMR perfusion studies have proven highly diagnostic for the detection of CAD relative to quantitative coronary angiography (QCA) [2] and fractional flow reserve (FFR) [3]. The aim of our prospective multicenter study is to assess the diagnostic performance of 3D CMR perfusion imaging in comparison with FFR.
Highlights
Cardiac magnetic resonance (CMR) perfusion imaging yields high diagnostic accuracy for the detection of coronary artery disease (CAD) [1]
Perfusion scans were obtained under adenosine stress (140 μg/kg/min for 6 min; 0.075 mmol/kg gadobutrol; Gadovist, Bayer Schering Pharma, Berlin, Germany) and at rest
fractional flow reserve (FFR) was recorded in all patent epicardial coronary arteries
Summary
Cardiac magnetic resonance (CMR) perfusion imaging yields high diagnostic accuracy for the detection of coronary artery disease (CAD) [1]. Standard 2D multislice CMR perfusion techniques only provide limited coverage and prohibit computation of myocardial ischemic burden. Two single-center 3D CMR perfusion studies have proven highly diagnostic for the detection of CAD relative to quantitative coronary angiography (QCA) [2] and fractional flow reserve (FFR) [3]. The aim of our prospective multicenter study is to assess the diagnostic performance of 3D CMR perfusion imaging in comparison with FFR
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