Abstract
Since its emergence reported in April 2009, pandemic influenza H1N1 rapidly spreads among humans all over the world. Although seasonal influenza vaccination has been implicated to occasionally induce skin diseases, extremely rare cases of skin eruption following pandemic influenza H1N1 vaccination have been reported. We here present a case of Mucha-Habermann disease-like eruption following pandemic influenza H1N1 vaccination. With a global H1N1 vaccination program against the pandemic H1N1 influenza, physicians and patients should be appraised of such rare skin reactions that may be induced by pandemic influenza H1N1 vaccination.
Highlights
Since its emergence reported in April 2009, pandemic influenza H1N1 rapidly spreads among humans all over the world
Human infections with pandemic influenza H1N1 virus were first identified in April 2009, and have been reported worldwide
The skin lesions developed only two days after vaccination, and arose on the trunk and extremities as well as the face, which is an uncommon location for Mucha-Habermann disease (MHD)
Summary
Since its emergence reported in April 2009, pandemic influenza H1N1 rapidly spreads among humans all over the world. A 51-year-old woman presented in October 2009 with a 19-day history of slightly itchy multiple erythematous papules on her face, trunk, and extremities. She had first noted these lesions two days after pandemic influenza H1N1 vaccination. Dermatological examination found multiple, disseminated, erythematous papules on the face, trunk, and extremities, some with central vesiculation, erosion, or hemorrhagic centers (Figures 1a-1c).
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