Abstract

Demyelinating diseases of the brain represent a complex group of neurological disorders characterised by the destruction of the myelin sheath surrounding nerve fibres, which disrupts neural transmission and leads to a wide range of neurological deficits1 . This article reviews the pathophysiology, radiologic features, and diagnostic criteria of key demyelinating disorders, including Multiple sclerosis (MS), Neuromyelitis optica, Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), Tumefactive demyelinating lesions, Acute necrotizing encephalopathy, and Krabbe disease. Advanced imaging techniques, particularly Magnetic resonance imaging (MRI), play a crucial role in the identification and differentiation of these diseases. Key MRI findings, such as T2-weighted hyperintense lesions in specific brain regions, contrast enhancement patterns, and lesion evolution, aid in diagnosis and disease monitoring. Radiologists play a vital role in early diagnosis, monitoring treatment response, and detecting complications, thereby guiding clinical management and improving patient outcomes in demyelinating brain diseases.

Full Text

Published Version

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.