MP-Gait: Fine-grained Parkinson's Disease Gait Impairment Assessment with Robust Feature Analysis

Abstract

Patients with Parkinson's disease (PD) often show gait impairments including shuffling gait, festination, and lack of arm and leg coordination. Quantitative gait analysis can provide valuable insights for PD diagnosis and monitoring. Prior work has utilized 3D motion capture, foot pressure sensors, IMUs, etc. to assess the severity of gait impairment in PD patients These sensors, despite their high precision, are often expensive and cumbersome to wear which makes them not the best option for long-term monitoring and naturalistic deployment settings. In this paper, we introduce mP-Gait, a millimeter-wave (mmWave) radar-based system designed to detect the gait features in PD patients and predict the severity of their gait impairment. Leveraging the high frequency and wide bandwidth of mmWave radar signals, mP-Gait is able to capture high-resolution reflected signals from different body parts during walking. We develop a pipeline to detect walking, extract gait features using signal analysis methods, and predict patients' UPDRS-III gait scores with a machine learning model. As gait features from PD patients with gait impairment are correctly and robustly extracted, mP-Gait is able to observe the fine-grained gait impairment severity fluctuation caused by medication response. To evaluate mP-Gait, we collected gait features from 144 participants (with UPDRS-III gait scores between 0 and 2) containing over 4000 gait cycles. Our results show that mP-Gait can achieve a mean absolute error of 0.379 points in predicting UPDRS-III gait scores.