MP73-17 THULIUM LASER EN-BLOC RESECTION OF BLADDER TUMOR (THUEB-BT): TIGER (THULIUM ITALIAN GROUP ESTABLISHED ON RESEARCH) STUDY TO COMPARE LASER AND ELECTRICAL EN- BLOC TRANSURETHRAL RESECTION OF BLADDER TUMOR

Abstract

You have accessJournal of UrologyBladder Cancer: Non-invasive IV (MP73)1 Apr 2020MP73-17 THULIUM LASER EN-BLOC RESECTION OF BLADDER TUMOR (THUEB-BT): TIGER (THULIUM ITALIAN GROUP ESTABLISHED ON RESEARCH) STUDY TO COMPARE LASER AND ELECTRICAL EN- BLOC TRANSURETHRAL RESECTION OF BLADDER TUMOR Raffaele Inzillo*, Giorgio Bozzini, Maruccia Serena, Antonio Luigi Pastore, Besana Umberto, Marco Amato, Luigi Bevilacqua, Paolo Parma, Giovanni Saredi, Stefano Casellato, Salvatore Micali, Bernardo Rocco, and Carlo Buizza Raffaele Inzillo*Raffaele Inzillo* More articles by this author , Giorgio BozziniGiorgio Bozzini More articles by this author , Maruccia SerenaMaruccia Serena More articles by this author , Antonio Luigi PastoreAntonio Luigi Pastore More articles by this author , Besana UmbertoBesana Umberto More articles by this author , Marco AmatoMarco Amato More articles by this author , Luigi BevilacquaLuigi Bevilacqua More articles by this author , Paolo ParmaPaolo Parma More articles by this author , Giovanni SarediGiovanni Saredi More articles by this author , Stefano CasellatoStefano Casellato More articles by this author , Salvatore MicaliSalvatore Micali More articles by this author , Bernardo RoccoBernardo Rocco More articles by this author , and Carlo BuizzaCarlo Buizza More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000959.017AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: En bloc resection of bladder tumors (EBRBT) may improve staging quality and perioperative morbidity and influence tumor recurrence. We want to evaluate the safety, efficacy, and recurrence rates of electrical versus Thulium laser en bloc resection of bladder tumors (THUEB-BT). METHODS: This Italian multicenter study included 362 patients at four tertiary centers in Lombardia. TUR-BT was performed with monopolar/bipolar current or Thulium laser energy. Staging quality measured by detrusor muscle involvement, tumor size, switch to conventional TURBT rate, early postoperative outcomes, hemoglobin loss and 18-month follow-up data were analyzed. RESULTS: Electrical EBRBT and THUEB-BT resection were used to treat 178 and 184 patients, respectively. Median tumor size was 1.9 cm; largest tumor was 4.4 cm. Detrusor muscle was present in 89.4%. A switch to conventional TURBT was significantly more frequent in the electrical en-bloc group (23.7 vs. 3.7%, p <0.05). Mean operation time, postoperative irrigation, catheterization time, and hospitalization were not different from a statistical point of view. Overall complication rate was low (Clavien ≥ 3, 3.3%). Post-operative hemoglobin values were significantly lower after electrical ERBT (p = 0.0013). Patient’s mean follow up was 20.3 months; 72 (19.8%) had recurrences. In total, 72.2% recurrences occurred outside the ERBT resection field, mainly for THUEB-BT. CONCLUSIONS: ERBT is safe and reliable regardless of the energy source and provides high-quality resections of tumors > 1 cm. Recurrence rates did not differ between groups, and the majority of recurrences occurred outside the ERBT resection field, mainly in THUEB-BT group. Source of Funding: No © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e1128-e1128 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Raffaele Inzillo* More articles by this author Giorgio Bozzini More articles by this author Maruccia Serena More articles by this author Antonio Luigi Pastore More articles by this author Besana Umberto More articles by this author Marco Amato More articles by this author Luigi Bevilacqua More articles by this author Paolo Parma More articles by this author Giovanni Saredi More articles by this author Stefano Casellato More articles by this author Salvatore Micali More articles by this author Bernardo Rocco More articles by this author Carlo Buizza More articles by this author Expand All Advertisement PDF downloadLoading ...