MP26-04 SAFETY, EFFICACY AND 12-MONTHS RECURRENCE RATE OF LASER VS. ELECTRICAL EN BLOC RESECTION OF UROTHELIUM CARCINOMA OF THE BLADDER: RESULTS OF THE EBRUC TRIAL

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You have accessJournal of UrologyBladder Cancer: Non-invasive I1 Apr 2015MP26-04 SAFETY, EFFICACY AND 12-MONTHS RECURRENCE RATE OF LASER VS. ELECTRICAL EN BLOC RESECTION OF UROTHELIUM CARCINOMA OF THE BLADDER: RESULTS OF THE EBRUC TRIAL Mario W. Kramer, Jens J. Rassweiler, Jan Klein, Alexey Martov, Nikolay Baykov, Rodolfo Hurle, Guenter Janetschek, Lukas Lusuardi, Mathias Wolters, Mahmoud Abbas, Armin Leitenberger, Markus Riedl, Udo Nagele, Axel S. Merseburger, Markus A. Kuczyk, Marko Babjuk, and Thomas R.W. Herrmann Mario W. KramerMario W. Kramer More articles by this author , Jens J. RassweilerJens J. Rassweiler More articles by this author , Jan KleinJan Klein More articles by this author , Alexey MartovAlexey Martov More articles by this author , Nikolay BaykovNikolay Baykov More articles by this author , Rodolfo HurleRodolfo Hurle More articles by this author , Guenter JanetschekGuenter Janetschek More articles by this author , Lukas LusuardiLukas Lusuardi More articles by this author , Mathias WoltersMathias Wolters More articles by this author , Mahmoud AbbasMahmoud Abbas More articles by this author , Armin LeitenbergerArmin Leitenberger More articles by this author , Markus RiedlMarkus Riedl More articles by this author , Udo NageleUdo Nagele More articles by this author , Axel S. MerseburgerAxel S. Merseburger More articles by this author , Markus A. KuczykMarkus A. Kuczyk More articles by this author , Marko BabjukMarko Babjuk More articles by this author , and Thomas R.W. HerrmannThomas R.W. Herrmann More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1126AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The quality of transurethral resection of bladder tumors strongly determines patient's tumor after-care and prognosis. En bloc resection of bladder tumors (ERBT) might improve staging quality, perioperative morbidity and influence tumor recurrence. This is the first European multi-center study which was initiated by ESUT and was conducted to evaluate the safety, efficacy and recurrence rates of electrical vs. laser ERBT. METHODS Transurethral ERBT was performed on 221 prospectively collected patients in six academic centers with either monopolar/bipolar current or holmium/thulium laser energy. Staging quality measured by detrusor muscle involvement, various perioperative/surgical parameters and 12 months follow-up data were analyzed. RESULTS 156 and 65 patients were treated with electrical and laser ERBT, respectively. Median tumor size was 2.1 cm with biggest up to 5 cm. Detrusor muscle was available in 97.3%. A switch to conventional TURBT was significantly more frequent in the electrical ERBT group (26.3% vs. 1.5%, p<0.001). Median operation duration (25 min), postoperative irrigation (1 day) and catheterization time (2 days) as well as hospitalization (3 days) were similar in both groups. Overall complication rate was low (Clavien ≥3, n=6 (2.7%)). Hemoglobin was significantly more decreased after electrical ERBT (p=0.0013), however overall hemoglobin loss was not clinically relevant (0.38 g/dl). 148 patients with first diagnosis of urothelium carcinoma of the bladder were followed for 12 months of which 33 (22.3%) recurred. 63.6% of recurrences occurred out of the ERBT resection field. No difference was noticed between both ERBT groups. CONCLUSIONS ERBT is safe and reliable regardless of the energy source used and offers high quality resections of tumors >1 cm. Recurrence rates did not differ within both groups although the majority of recurrences were noticed out of the ERBT resection field. Laser device might be an alternative for the treatment of patients with higher risk of postoperative bleeding due to its efficient hemostatic effect. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e294 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mario W. Kramer More articles by this author Jens J. Rassweiler More articles by this author Jan Klein More articles by this author Alexey Martov More articles by this author Nikolay Baykov More articles by this author Rodolfo Hurle More articles by this author Guenter Janetschek More articles by this author Lukas Lusuardi More articles by this author Mathias Wolters More articles by this author Mahmoud Abbas More articles by this author Armin Leitenberger More articles by this author Markus Riedl More articles by this author Udo Nagele More articles by this author Axel S. Merseburger More articles by this author Markus A. Kuczyk More articles by this author Marko Babjuk More articles by this author Thomas R.W. Herrmann More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...