MP45-20 PREVALENCE AND CLINICAL PROFILE OF VERY YOUNG MEN WITH ERECTILE DYSFUNCTION - FINDINGS FROM A REAL-LIFE CROSS-SECTIONAL STUDY

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You have accessJournal of UrologyCME1 Apr 2023MP45-20 PREVALENCE AND CLINICAL PROFILE OF VERY YOUNG MEN WITH ERECTILE DYSFUNCTION - FINDINGS FROM A REAL-LIFE CROSS-SECTIONAL STUDY Edoardo Pozzi, Federico Belladelli, Giuseppe Fallara, Simone Cilio, Christian Corsini, Francesco Lanzaro, Alessandro Bertini, Massimiliano Raffo, Fausto Negri, Ludovica Cella, Margherita Fantin, Luigi Candela, Paolo Capogrosso, Luca Boeri, Alessia D'arma, Francesco Montorsi, and Andrea Salonia Edoardo PozziEdoardo Pozzi More articles by this author , Federico BelladelliFederico Belladelli More articles by this author , Giuseppe FallaraGiuseppe Fallara More articles by this author , Simone CilioSimone Cilio More articles by this author , Christian CorsiniChristian Corsini More articles by this author , Francesco LanzaroFrancesco Lanzaro More articles by this author , Alessandro BertiniAlessandro Bertini More articles by this author , Massimiliano RaffoMassimiliano Raffo More articles by this author , Fausto NegriFausto Negri More articles by this author , Ludovica CellaLudovica Cella More articles by this author , Margherita FantinMargherita Fantin More articles by this author , Luigi CandelaLuigi Candela More articles by this author , Paolo CapogrossoPaolo Capogrosso More articles by this author , Luca BoeriLuca Boeri More articles by this author , Alessia D'armaAlessia D'arma More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Andrea SaloniaAndrea Salonia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003291.20AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Erectile dysfunction (ED) is a relatively common complaint among young men. Prevalence and risk factors of very young men (defined as men younger than 29 yr of age at first presentation) with ED has been scantly analysed. We aimed to assess and compare the sociodemographic and clinical characteristics of young (30-40 yr) and very young (18-29 yr) ED patients and to explore the changes in patterns of reported ED in men with ≤ 29 yr over a 17-yr period at a single academic centre. METHODS: Data from 519 consecutive patients < 40 yr of age at first presentation for ED as their primary compliant between 2005 and 2022 were analysed. Health significant comorbidities were scored with the Charlson Comorbidity Index (CCI). All patients completed the IIEF. Patients were segregated into two groups: 18-29 vs. 30-40 yr. Descriptive statistics tested sociodemographic and clinical differences between the two cohorts. Linear regression and local polynomial models were applied to explore and graphically display the trend of assessing 18-29 vs. 30-40-yr ED patients over the analysed time frame. RESULTS: Overall, 191 (36.8%) were < 29 yr and 328 (63.2%) were 30-40 yr. The two groups did not differ in terms of commonly recognised ED risk factors (CCI, regular physical exercise and regular alcohol use). Rates of severe ED (IIEF-EF<11) did not differ between the two cohorts at presentation (20.9% vs. 18.6%) respectively. Conversely, younger patients were less likely to report a stable partner (45.5% vs. 61.6%, p<0.001), to suffer of arterial hypertension (3.7% vs. 8.5%, p=0.04) and had lower BMI (22.8 vs. 24.5 kg/m2, p<0.001) but higher total testosterone (5.6 vs. 5.1 ng/mL, p=0.01), respectively. At linear regression analysis, patients assessed throughout the 17-yr time frame were progressively younger (Coeff –0.09, p<0.001). Figure 1 graphically displays the probability of assessing younger patients over the 17-yr time frame with median (IQR) age in 2005 of 34 (32-34) yr vs. 29 (25-32) yr in 2022. CONCLUSIONS: Among young men seeking first medical help for new onset ED, one out of three has less than 29 yr. Of those, one out of five reports criteria suggestive of severe ED. The probability of assessing very young men complaining of ED (18-29 yr) has worrisomely increased over the last two decades. Source of Funding: © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e629 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Edoardo Pozzi More articles by this author Federico Belladelli More articles by this author Giuseppe Fallara More articles by this author Simone Cilio More articles by this author Christian Corsini More articles by this author Francesco Lanzaro More articles by this author Alessandro Bertini More articles by this author Massimiliano Raffo More articles by this author Fausto Negri More articles by this author Ludovica Cella More articles by this author Margherita Fantin More articles by this author Luigi Candela More articles by this author Paolo Capogrosso More articles by this author Luca Boeri More articles by this author Alessia D'arma More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement PDF downloadLoading ...