MP40-10 COMPLETE BLOOD COUNT PARAMETERS AS A PREDICTOR OF TESTICULAR SURVIVAL FOLLOWING ACUTE TESTICULAR TORSION IN CHILDREN

Abstract

You have accessJournal of UrologyPediatrics: Testis & Varicoceles, Stones1 Apr 2015MP40-10 COMPLETE BLOOD COUNT PARAMETERS AS A PREDICTOR OF TESTICULAR SURVIVAL FOLLOWING ACUTE TESTICULAR TORSION IN CHILDREN Cagatay E. Afsarlar, Engin Yilmaz, Yilmaz Aslan, Jason Au, Irina Stanasel, David Roth, and Chester J. Koh Cagatay E. AfsarlarCagatay E. Afsarlar More articles by this author , Engin YilmazEngin Yilmaz More articles by this author , Yilmaz AslanYilmaz Aslan More articles by this author , Jason AuJason Au More articles by this author , Irina StanaselIrina Stanasel More articles by this author , David RothDavid Roth More articles by this author , and Chester J. KohChester J. Koh More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1192AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Complete blood count (CBC) provides simple systemic inflammatory response parameters such as white blood cell count (WBC), neutrophil count, lymphocyte count, neutrophil/lymphocyte (N/L) ratio, and platelet/lymphocyte (P/L) ratio. Previous clinical studies have demonstrated increased N/L and P/L ratios following ischemic conditions. The objective of this study was to determine if CBC parameters could predict the eventual survival of torsed testicles. METHODS A retrospective chart review of patients with acute testicular torsion between January 2009 and October 2014 was conducted. Patients with a preoperative CBC were identified and included in the study while those without a CBC were excluded. Patient demographics, duration of pain, CBC parameters, imaging studies, type of surgical procedure, and follow-up were assessed. Patients with clinical and radiographic evidence of acute epididymitis and torsed testicular and epididymal appendages were excluded. RESULTS A total of 184 patients with acute testicular torsion were identified, and 27 patients with a preoperative CBC were identified. Scrotal exploration was performed if absent or decreased blood flow was demonstrated by Doppler US or if indicated by clinical history and exam. Median patient age was 12.6 years. Nine patients underwent detorsion and fixation, and 18 patients underwent orchiectomy. Concomitant contralateral testicular fixation was performed in all patients. Duration of pain, WBC, and neutrophil count were significantly higher in orchiectomy patients (p=0.003, p=0.006, and p=0.012, respectively) as compared to patients who had a detorsed testis. Additionally, 86.7% of orchiectomy patients had an elevated WBC count >10,000 as compared to only 13.3% of detorsion patients (p=0.014). There was no significant difference in terms of N/L and P/L ratio between the groups (p=0.28, and p=0.797, respectively). CONCLUSIONS Since CBC is a simple and cost effective study that is widely available, CBC parameters (WBC and neutrophil count) can be utilized to help predict the outcome of a torsed testicle. This can be helpful to determine the urgency of the scrotal exploration when available surgical time is limited. A significant difference of N/L and P/L ratios was not demonstrated as seen in previous studies. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e466 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Cagatay E. Afsarlar More articles by this author Engin Yilmaz More articles by this author Yilmaz Aslan More articles by this author Jason Au More articles by this author Irina Stanasel More articles by this author David Roth More articles by this author Chester J. Koh More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...