MP20-03 RENAL PARENCHYMAL VOLUME DOES NOT APPROXIMATE RENAL FUNCTION IN STONE FORMING PATIENTS

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You have accessJournal of UrologyStone Disease: Basic Research I1 Apr 2014MP20-03 RENAL PARENCHYMAL VOLUME DOES NOT APPROXIMATE RENAL FUNCTION IN STONE FORMING PATIENTS Timothy Durso, Adam Kadlec, Gopal Gupta, Humberto Martinez-Suarez, and Thomas Turk Timothy DursoTimothy Durso More articles by this author , Adam KadlecAdam Kadlec More articles by this author , Gopal GuptaGopal Gupta More articles by this author , Humberto Martinez-SuarezHumberto Martinez-Suarez More articles by this author , and Thomas TurkThomas Turk More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.725AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES In healthy kidneys, renal parenchymal volume (RPV) correlates with renal function and anthropometric measurements such as body surface area. These same correlations for RPV among stone forming patients are less certain. 3-dimensional volume rendering (3DV) was used to investigate the relationship between RPV, renal function, and anthropometric measurements in stone forming patients. METHODS Age, gender, height, body weight, body mass index, and serum creatinine were recorded for 140 patients with a history of stone formation. Body surface area was calculated using the equation of Dubois and Dubois. Creatinine clearance and glomerular filtration rate were calculated using the Cockcroft-Gault equation and modification of diet in renal disease equation, respectively. RPV was measured using three-dimensional rendering from computed tomography scans. RPV was then assessed for correlations with measurements as stated earlier. RESULTS Mean total RPV in all patients was 342.8 ± 76.2 mL. RPV correlated positively with body weights and measures, but not with age (r = .074, p = .304). Mean RPV in men did not differ from women after indexing for body surface area (172.1 vs. 170.2 mL/m2, p =.854). Patients aged 60 and older had smaller RPV indexed for body surface area than younger patients (161.1 vs. 175.7 mL/m2, p = .007). The only RPVs that correlated with kidney function were from patients older than 60. RPV in this population correlated positively with Cockcroft-Gault creatinine clearance (r = .447, p = .008). CONCLUSIONS In a population of patients with a history of stone formation, RPV correlates with anthropometric measurements and age, but not with renal function. Therefore, RPV is not an appropriate surrogate for renal function in stone forming patients. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e197 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Timothy Durso More articles by this author Adam Kadlec More articles by this author Gopal Gupta More articles by this author Humberto Martinez-Suarez More articles by this author Thomas Turk More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...