MP16-04 LASER VERSUS ELECTRICAL E-BLOC RESECTION OF BLADDER TUMORS FOR TREATMENT OF NON-MUSCLE INVASIVE BLADDER CANCER; CRITICAL APPRAISAL THROUGH A RANDOMIZED TRIAL

Abstract

You have accessJournal of UrologyBladder Cancer: Non-invasive II (MP16)1 Sep 2021MP16-04 LASER VERSUS ELECTRICAL E-BLOC RESECTION OF BLADDER TUMORS FOR TREATMENT OF NON-MUSCLE INVASIVE BLADDER CANCER; CRITICAL APPRAISAL THROUGH A RANDOMIZED TRIAL Ahmed Elshal, Mohamed Bahy, Mahmoud Laymon, Abdelwahab Hashem, Ahmed Mosbah, and Adel Nabeeh Ahmed ElshalAhmed Elshal More articles by this author , Mohamed BahyMohamed Bahy More articles by this author , Mahmoud LaymonMahmoud Laymon More articles by this author , Abdelwahab HashemAbdelwahab Hashem More articles by this author , Ahmed MosbahAhmed Mosbah More articles by this author , and Adel NabeehAdel Nabeeh More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002001.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Laser En-bloc resection of bladder tumors (ERBT) has been reported as a safer procedure with less residual tumor and better specimen quality when compared to conventional resection. In this trial, we tested the non-inferiority of electrical versus laser ERBT invasive bladder cancer (NMIBC) METHODS: Between June 2019 and December 2020, 106 patients with cystoscpic visual criteria of NMIBC were randomly allocated to laser and electrical enbloc resection. The primary endpoint was to assess the need of conversion to conventional TURBT. Operative parameters, quality of specimen, perioperative complications and completeness of resection as indicated by residual tumors in restaging TUR (2-6 weeks after ERBT) Trial ID NCT04029948 RESULTS: Patients` and tumor`s baseline characteristics were comparable in both groups. More resection time was reported during laser ERBT, p= 0.04. Technical failure with conversion to conventional resection was in 2 cases during electrical ERBT and none during Laser ERBT, P=0.146 Detrusor muscle was sampled in 59.3% and 53.8% (p=0.574) in Laser ERBT and electrical ERBT, respectively. Lamina propria invasion was 85.1%% and 84% in Laser ERBT and electrical ERBT, respectively (p=0.111). Intraoperative complications were reported in 17.3% after electrical ERBT in the form of obturator kick, bladder perforation and with no complications reported in the laser group (p=0.002). Table 1 There was no statistical difference between laser and electrosurgical ERBT regarding urethral catheter duration and hospital stay with p value 0.2 & 0.9 in the 2 groups respectively. Residual tumors at second look were detected in 6.5% and 2.6% Laser ERBT and electrical ERBT, respectively (p=0.391). CONCLUSIONS: Laser ERBT seems to be safer procedure for bladder tumor resection with longer resection time when compared to electrical ERBT. Source of Funding: no © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e297-e297 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ahmed Elshal More articles by this author Mohamed Bahy More articles by this author Mahmoud Laymon More articles by this author Abdelwahab Hashem More articles by this author Ahmed Mosbah More articles by this author Adel Nabeeh More articles by this author Expand All Advertisement Loading ...