Abstract

Outcomes assessed included 30-day mortality, surgical site infection (SSI), MI, DVT/PE, Clavien IV complications, length of stay (LOS), and combined adverse events. Chi-square analysis was used for comparing categorical variables, Kruskal-Wallis for non-parametric continuous variables, and logistic regression for comparing different clinical tests. RESULTS: Increasing FI was significantly associated with Clavien IV complications, number of SSI and all combined adverse events (p<0.05 for all). A Kruskal-Wallis H test demonstrated a statistically significant difference in LOS between those with different FI (c 1⁄4 88.02, p<0.01) with a mean rank of 3, 4, 6, 5, 2 and 1 day(s) for FI of 1, 2, 3, 4, 5 and 6 respectively. Multivariate analysis indicated that FI was significantly correlated with Clavien IV complications (OR 1.368, p< 0.01), MI (OR 2.745, p < 0.01), and adverse events including SSI, UTIs and DVT/PE (OR 1.371, p <0.01). CONCLUSIONS: Using a large national database, a modified frailty index was shown to significantly correlate with 30-day morbidity and length of stay after RP but not with mortality. This simple tool may be useful for both risk assessment and surgical planning, especially in elderly patients with multiple comorbidities.

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