Abstract
A significant percentage of candidates to prostate biopsy are initially negative but some of them continue with increased PSA level or abnormal DRE. There exists controversy about management in patients with first negative biopsy and persistent suspicion of prostate cancer, and which biopsy model is optimal. Recently saturation biopsy schemes (20-26 cores) appear more effective to detect prostate cancer in patients with repeat biopsy. The aim of this study is to compare ten cores biopsy or saturation biopsy in patients with repeat biopsy.
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